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KMID : 1137820080290020107
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2008 Volume.29 No. 2 p.107 ~ p.113
Rotating-Gantry-Based X-Ray Micro-Tomography System with the Sliding Mechanism Capable of Zoom-In Imaging
Cho Min-Hyoung

Lee Dong-Hun
Han Byung-Hee
Lee Soo-Yeol
Abstract
We introduce a rotating-gantry-based x-ray micro-tomography system to be used for small animal imaging studies. It has the zoom-in imaging capability for high resolution imaging of a local region inside the animal subject without any contrast anomalies arising from truncation of the projection data. With the sliding mechanism mounted on the rotating gantry holding the x-ray source and the x-ray detector, we can control the magnification ratio of the x-ray projection data. By combining the projection data from the large field of view (FOV) scan of the whole animal subject and the projection data from the small FOV scan of the region of interest, we can obtain artifact-free zoomed-in images of the region of interest. For the acquisition of x-ray projection data, we use a 1248¡¿1248 flat-panel x-ray detector with the pixel pitch of 100 mm. It has been experimentally found that the developed system has the spatial resolution of up to 121p/mm when the highest magnification ratio of 5:1 is applied to the zoom-in imaging. We present some in vivo rat femur images to demonstrate utility of the developed system for small animal imaging.
KEYWORD
micro-tomography, zoom-in imaging, small animal imaging, rotating gantry, flat panel detector
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